Ichimaru Pharcos recently launched its latest active ingredient for skin care called “IZAYOI.” Now, don’t be deceived by the name, for though it’s alien-sounding, it is actually derived from the fruit of the delicate rose. Yes, the flower that we all know and love. You might wonder how the lovely rose came to have “fruit”, but this is not your ordinary rose. IZAYOI is an extract of Rosa Roxburghii Tratt f. normalis, more commonly known as “chestnut rose”. The fruits are globular and very hairy and thorny and resemble chestnut, thus, the name.

The fruit of Rosa Roxburghii, from which IZAYOI is extracted, contains very high levels of vitamins and minerals, especially vitamins C and P, flavanoids and other bio-active compounds. The vitamin C content of chestnut rose fruits is about 120 times higher than that of citrus fruits.¹

It is proved that the fruit juice can halt or reverse the growth of cancers, may enhance immunity and can be used to combat stress and aging. Moreover, considerable high superoxide dismutase (SOD) can be detected in this fruit.²

Technical Background

Ageing skin is more sensitive to UV. The minimum erythemal dose or MED decreases with age. Because of this, keratinocytes are easily damaged and their survival rate becomes drastically lower. But that’s not the end of it. Dead keratinocytes could wreak havoc on the skin. They release “damage-associated molecular patterns” or DAMPs. These DAMPs, in turn, initiate inflammation in surrounding live cells. DAMPs are involved in the earliest stage of skin aging due to UV exposure.

IZAYOI Activity

Based on the characteristic features of chestnut rose fruit discussed above, IZAYOI, an extract of the fruit, has been developed to prevent skin aging caused by UV, especially for women age 40 and above. Specifically, IZAYOI inhibits UV-induced inflammation brought about by DAMPs.

IZAYOI is a very promising anti-aging active that is worth further study and development in skin care products.

To request for complete in vitro and in vivo studies of IZAYOI, please call Actichem office. Or request for a product presentation by one of our technical representatives.

Additionally, IZAYOI won both the Active Ingredients Award and the R&D Award during the Personal Care and Homecare Ingredients 2017 in Guangzhou, China.

 

References:

¹,² Globalsciencebooks.info